Error '80004005' , Exception occured in Microsoft JET Database Engine

Hi,

  I am using Microsoft Jet 4.0 OLE DB Provider for storing into Microsoft 2000 database file (.mdb file) for the past couple of months without any issue, now I am getting the Error '80004005' , Exception occured in Microsoft JET Database Engine: Cannot open database. It may not be a database that your application recognizes, or the file may be corrupt. I did study some forums but couldn't get any definite answer as to why this could happen. 

  Please help me in understanding this error so that I can avoid losing data in future.

Thanks 

Mukunda