Control simulation loop vs. Traditional while loop

Dear

I really confuse about the difference between control simulation loop and traditional while loop 

their is no an information about such difference in NI web or user guide 

The labview Control and Simulation Module contains a block diagram  for simulation of linear and nonlinear continuous-time and discrete-time dynamic systems

but also we can use  traditional while loop  for simulation of linear and nonlinear continuous-time and discrete-time dynamic system 

so what are the difference ??

is my information for  traditional while loop  is wrong ???

 please for any member can list his difference as he see to see all possible differences 

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thank in advance

best regards